Bibliography for Article and Presentation

“Emerging Concepts in Obesity”

by Robert Woodbury, MD April, 2014


  • Centers for Disease Control. Obesity trends 2010
  • Ryan, Woods, and Seeley “Central nervous system mechanisms linking consumption of palatable high-fat diets to the defense of greater adiposity” Cell Metab. 2012 Feb 8;15(2) 137-149.
  • Seeley et al “Behavioral, endocrine, and hypothalamic responses to involuntary overfeeding.” Am J. PHysiology, Sept 1996 vol 271. 819-823.
  • Williams Trust Case Control Consortium. “Genomic-wade association study of 14,000 cases of seven common diseases and 3000 shared controls”. Nature 2007; 447: 661-678
  • Frayling et al.  “A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity”.  Science 2007. 316. 889-894
  • Cecil JE.  “An obesity associated FTO gene variant and increased energy intake in children”  NEJM 2008: 359: 2558-2566
  • Diva, C. “Variation in the FTO contributes to childhood obesity and severe adult obesity”.  Nat. Genet. 2007: 39; 724-726
  • Andreasen, CH.  “Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation”.  Diabetes 2008; 57: 95-101
  • Hunt, SC. “Association of the FTO gene with BMI”.  Obesity Apr 2008 16(4) 902
  • Karra et al. “A link between FTO, ghrelin, and impaired brain food-cue responsivity.”  J. Clin. Inv. Aug 2013 123(8) 3539-3551
  • Tamashiro et al.  “Cloned mice have an obese phenotype not transmitted to their offspring.”  Nat Medicine Mar 2002 8(3)
  • Smith, Marceau, et al.  “Effects of maternal surgical weight loss in mothers on the intergenerational transmission of obesity”.  J. Clin Endocrinol Metab. 2009 94(11) 4275
  • Kral, Marceau et al.  “Large maternal weight loss from obesity surgery prevents transmission of obesity to children who were followed for 2 to 18 years”.  Pediatric 2006 Dec 118 (6) e1644
  • Woodard, Morton, et al.  “Probiotics improve outcomes after Roux-en-Y Gastric Bypass surgery: A prospective randomized trial. “  J. Gastrointest Surgery 2009 13:1198-1204
  • Lio, Kaplan et al. “Conserved shifts in gut microbiome due to gastric bypass reduce host weight and adiposity”.  Sci Transl Med 2013 5:178
  • Molinaro et al. “Probiotics, prebiotics, energy balance, and obesity”.  Gastroenterol Clin N Am 2012 (41)843-854
  • Jumperts  “Energy balance studies reveal associations between gut microbes, caloric load, and nutrient absorption in humans. “  Am J Clin Nutr Jul 2011 94(1):58-65
  • Jayasena et al  “Role of gut hormones in obesity”.  Endocrinology and Metabolism Clinics of N AM 2008 37: 769-787
  • Mikalakis and le Roux  “Gut hormones and leptin: Impact on energy control and changes after bariatric surgery – what the future holds. “  Obes Surg 2012 22: 1648-1657
  • Gallwitz and Schmidt  “GLP-1 receptor knock-out causes glucose intolerance but no alterations of eating behavior”.  Z Gastroenterolgy 1997; 35: 655
  • Cohen et al.  “Effect of gastric bypass surgery in patients with type 2 diabetes and only mild obesity”.  Diabetes Care 2012; 35(7) 1420-1428
  • Sumithran et al.  “Long term persistence of hormonal adaptations to weight loss”.  NEJM 2011 365(17) 1597-1604
  • ORourke,Robert OHSU. Presentation at ASMBS 2012. Based on his article.  O’Rourke “Inflammation in obesity-related disease. Surgery 2009 March; 145(3) 255-259
  • Speaker and Fleshner. “Interleukin-1 Beta: a potential link between stress and the development of visceral obesity. BMC Physiology 2012 12:8
  • Ahima et al.  “Brain regulation of appetite and satiety”.  Endocrin Metab Clinics N. Am. 2008 (37)811
  • Mikalakis and leRoux.  “Gut hormones and leptin: Impact on energy control and changes after bariatric surgery, what the future holds.” Obes Surg 2012 22:1648-1657
  • Seeley and Kaplan. Presentation at Metabolic Applied Research Strategy Conference June 2010
  • Kaplan. “Effect of surgical and non-surgical weight loss on energy expenditure”. Presentation at Metabolic Applied Research Strategy, June 2012.  Based on much of his own unpublished and published work including: Mirshahi et al “The MC4R Allele is associated with better metabolic status and more weight loss after gastric bypass surgery. J Clin Endocrin Metab Dec 2011; 96(12) E2088-E2096
  • Hatoum et al.  “Melanocortin-4 receptor signaling is required for weight loss after gastric bypass surgery” J. Clin Endocrinolgy Metab 2012
  • Periera, et al. “Effects of a low glycemic load diet on resting energy expenditure and heart disease risk factors during weight loss. JAMA. Nov 24, 2004. vol 292 #20
  • Stylopoulous et al  “Roux-en-Y gastric bypass enhances energy expenditure and extend lifespan in diet-induced obese rats”.  Obesity 2009; 17(10): 1839-1847
  • Shin et al.  “Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after roux-en-y gastric bypass surgery in high fat fed obese rats.”  Obesity surg Apr 2013; 23(4) 531-540

Our Favorite Books

  • “Eat Drink and be Healthy” Walt Willett
  • “KMD: Ketogenic Mediterranean Diet” Steve Parker
  • “Omnivore’s Dilemma” Michael Pollan
  • “Bloog Sugar Solution” Mark Hyman
  • “Wheat Belly” William Davis
  • “Changing for Good”
  • “Food, Inc.” Karl Weber

Our Favorite Cookbooks

  • “Practical Paleo” Diane Sanfilippo
  • “Against All Grain” Danielle Walker
  • “Nom Nom Paleo” Michelle Tam